GNAS (R201H Mutant) antibody-多抗-深圳欣博盛生物科技有限公司

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GNAS (R201H Mutant) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX135413	规格：100μl	目录价：￥4000
货号：GTX135413-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GNAS (R201H Mutant) antibody

别名:

GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus , 5530400H20Rik , A930027G11Rik , C130027O20Rik , GPSA , GSP , Galphas , Gnas1 , Gnasxl , Gs-alpha , Gsa , Nesp , Nesp55 , Nespl , Oed-Sml , Oedsml , P1 , P2 , P3 , PHP1A , PHP1B , POH , SCG6

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ICC/IF, WB

同种型:

IgG

免疫原:

Carrier-protein conjugated synthetic peptide surrounding mutant R201H of mouse GNAS. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.4 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.

生产商:

GeneTex

功能与背景:

This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, which is commonly found in imprinted genes and correlates with transcript expression. This gene has an antisense transcript. One of the transcripts produced from this locus, and the antisense transcript, are both paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Additional transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2015]

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