GnRH-Receptor Antibody / LHCG Receptor-单抗-深圳欣博盛生物科技有限公司

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GnRH-Receptor Antibody / LHCG Receptor

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5532SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

GnRH-Receptor Antibody / LHCG Receptor

产品描述:

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA

同种型:

Mouse IgG1, kappa

免疫原:

amino acids MANSASPEQNQHCSAINNSIPLMQGNLPY from the N-terminal of human GnRH receptor was used as the immunogen for the GnRH-Receptor antibody.

克隆性:

Monoclonal (mouse origin)