| 货号:79-882 | 规格:0.1 mg | 目录价:¥6598.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GRB2 (phospho Ser159) Antibody
别名:
GABJ, KIAA0571, pp100
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
The antibody detects endogenous levels of GRB2 only when phosphorylated at serine 159.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
Store antibody at -20˚C for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产地:
美国
生产商:
Prosci
功能与背景:
This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Accession #:
NP_536739.1
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