| 货号:GTX48612 | 规格:50μl | 目录价:¥6600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GSK3 beta (phospho Ser9) antibody
别名:
glycogen synthase kinase 3 beta
反应种属:
Bovine, Chicken, Dog, Human, Mouse, Primate, Rat, Xenopus, Zebrafish
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
Specific for the ~46k GSK3 beta protein phosphorylated at Ser9. Also weakly labels the ~51k GSK3 alpha band due to the high degree of homology between the 2 subunits. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
同种型:
IgG
免疫原:
Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer9 of GSK3 beta.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
47
产品形式:
Liquid
存储溶液:
10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]
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