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折扣/货期| 货号：SIH-451-25MG | 规格：25 mg | 目录价：￥6509 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GW5074
别名:
3-(3,5-Dibromo-4-hydroxybenzyliden)-5-iodo-1,3-dihydroindol-2-one
产品描述:
c-Raf1 kinase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
520.9
产品形式:
Yellow to orange solid
产地:
加拿大
功能与背景:
GW5074 is a potent and selective c-Raf1 kinase inhibitor. GW5074 shows ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. GW5074 has been shown to block low potassium induced cell death, as well as, prevent neurodegeneration. GW5074 is cell-permeable.
纯度:
≥98% (TLC)
来源:
Synthetic
CAS号:
220904-83-6
分子式:
C15H8Br2INO2
溶解度:
Soluble to 1 mM in ethanol and to 100 mM in DMSO
PubChem CID:
5924208
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