H-Ras antibody [H-RAS-03]-单抗-深圳欣博盛生物科技有限公司

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H-Ras antibody [H-RAS-03]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80140

规格：100μg

目录价：￥4700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

H-Ras antibody [H-RAS-03]

别名:

CBAS/HAS , CHARAS1 , CHRAS , CTLO , HAMSV , HRAS , HRAS1 , HRASIDX , HRas protooncogene, GTPase , RASH1 , p21ras , H-Ras , HRas proto-oncogene, GTPase

反应种属:

Human

宿主来源:

Mouse

实验应用:

同种型:

IgG1

免疫原:

Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein

克隆性:

Monoclonal

克隆号:

H-RAS-03

纯化方式:

Protein A purified

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]

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