H3.3G34R Mononucleosome, Biotinylated-突变/修饰核小体-深圳欣博盛生物科技有限公司

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H3.3G34R Mononucleosome, Biotinylated

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：16-0346

规格：50 µg

目录价：￥5700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

H3.3G34R Mononucleosome, Biotinylated

产品描述:

H3.3 is a histone variant found in regions of high chromatin turnover outside of S-phase (e.g. at actively transcribed genes). The substitution of R for G at position 34 of H3.3 interferes with SETD2-mediated H3K36 methylation. This mutation has been associated with bone cancers and astrocytomas[1]. H3.3G34R Mononucleosomes consist of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of H2A, H2B, H3.3G34R and H4) to form a nucleosome, the basic repeating unit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [2], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA in this nucleosome contains a 5’ biotin-TEG group.

宿主来源:

Human

表达系统:

E. coli & synthetic DNA

保存温度:

Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.

运输温度:

Dry ice.

产品形式:

0.964 mg/mL nucleosome in 51.9 µL 10 mM Tris HCl pH 7.5, 25 mM NaCl, 1 mM EDTA, 2 mM DTT, 20% glycerol. (27.3 µg protein weight, 50 µg DNA + protein)

产地:

美国