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折扣/货期| 货号：F54120-0.05ML | 规格：0.05 ml | 目录价：￥2962.25 |
| 货号：F54120-0.2ML | 规格：0.2 ml | 目录价：￥6343.55 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HACE1 Antibody
产品描述:
HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 is an E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB. [UniProt]
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
同种型:
Mouse IgG1, kappa
免疫原:
Recombinant human HACE1 was used as the immunogen for the HACE1 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
1854CT757.66.47
纯化方式:
Protein G purified
保存温度:
Aliquot the HACE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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