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折扣/货期| 货号：F54116-0.05ML | 规格：0.05 ml | 目录价：￥2962.25 |
| 货号：F54116-0.2ML | 规格：0.2 ml | 目录价：￥6343.55 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CRY2 Antibody / Cryptochrome 2
产品描述:
Cryptochrome 2 is a transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). CRY1 and CRY2 have redundant functions but also differential and selective contributions at least in defining the pace of the SCN circadian clock and its circadian transcriptional outputs. CRY2 is a less potent transcriptional repressor in cerebellum and liver than CRY1, though less effective in lengthening the period of the SCN oscillator and seems to play a critical role in tuning SCN circadian period by opposing the action of CRY1. [UniProt]
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
WB
同种型:
Mouse IgG1, kappa
免疫原:
Recombinant human Cryptochrome 2 was used as the immunogen for the CRY2 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
1819CT334.92.36.9
纯化方式:
Protein G purified
保存温度:
Aliquot the CRY2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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