HDAC3 Antibody-单抗-深圳欣博盛生物科技有限公司

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HDAC3 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9743SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

HDAC3 Antibody

产品描述:

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FACS, IF

同种型:

Mouse IgG2b

免疫原:

Recombinant full-length human HDAC3 protein was used as the immunogen for the HDAC3 antibody.

克隆性:

Monoclonal (mouse origin)