| 货号:RQ7635 | 规格:100 ug | 目录价:¥6488 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
hDKIR Antibody / C3IP1 / KLHL12
产品描述:
Kelch-like protein 12, also called CUL3-interacting protein 1 (C3IP1) and DKIR homolog (hDKIR), is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB, IHC-P
同种型:
Mouse IgG2a
免疫原:
E. coli-derived recombinant human protein (amino acids R27-I331) was used as the immunogen for the hDKIR antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
2G11D1
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the hDKIR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
促销活动
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