| 货号:RQ7632 | 规格:100 ug | 目录价:¥6488 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RNF20 Antibody / BRE1A
产品描述:
E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
同种型:
Mouse IgG2b
免疫原:
E. coli-derived recombinant human protein (amino acids E123-S389) was used as the immunogen for the RNF20 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
3C6E2
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the RNF20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
促销活动
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