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折扣/货期| 货号：V8782-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V8782-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HGAL Antibody / GCSAM / GCET2
产品描述:
Germinal center-associated signaling and motility protein / GCSAM, also called GCET2 and HGAL or hGAL, contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG1, kappa
免疫原:
A portion of amino acids 1-200 was used as the immunogen for the HGAL antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
HGAL/830
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the HGAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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