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折扣/货期| 货号：GTX25402 | 规格：100μl | 目录价：￥6300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HIP1 antibody [4B10]
别名:
huntingtin interacting protein 1 , HIP-I , ILWEQ , SHON , SHONbeta , SHONgamma
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ChIP assay, ICC/IF, IHC-P, IP, WB
靶标/特异性:
We do not recommend use of this product for Rat.
同种型:
IgG1
免疫原:
Human 3'-HIP1 (~65 kDa)
克隆性:
Monoclonal
克隆号:
4B10
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
116
产品形式:
Liquid
存储溶液:
Ascites, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]
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