HLA-A2 antibody [BB7.2]-单抗-深圳欣博盛生物科技有限公司

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HLA-A2 antibody [BB7.2]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX75803

规格：200μg

目录价：￥6500

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HLA-A2 antibody [BB7.2]

别名:

Major Histocompatibility Complex, Class I, A , Hlaa , Hla-A

反应种属:

Human

宿主来源:

Mouse

实验应用:

FCM, IHC-Fr, IP

靶标/特异性:

The epitope recognized by this antibody has been studied extensively and would appear to include the carboxy-terminus of the alpha-2 helix and a turn on one of the underlying beta strands.

同种型:

IgG2b

免疫原:

Papain solubilised HLA-A2

克隆性:

Monoclonal

克隆号:

BB7.2

纯化方式:

Protein G purified

偶联:

Unconjugated

产品浓度:

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]

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