HLA-B Antibody-单抗-深圳欣博盛生物科技有限公司

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HLA-B Antibody

品牌：NSJ Bio

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说明书

折扣/货期

货号：F40002-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40002-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HLA-B Antibody

产品描述:

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, ELISA

同种型:

Mouse IgM

免疫原:

A portion of amino acids 62-90 from the human protein was used as the immunogen for this HLA-B antibody.

克隆性:

Monoclonal (mouse origin)