HLA-E Antibody / MHC class I antigen E-单抗-深圳欣博盛生物科技有限公司

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HLA-E Antibody / MHC class I antigen E

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5733SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

HLA-E Antibody / MHC class I antigen E

产品描述:

Major histocompatibility complex (MHC) molecules, which include human leukocyte antigens (HLAs), form an integral part of the immune response system. They are cell-surface receptors that bind foreign peptides and present them to cytotoxic T lymphocytes (CTLs). MHC class I molecules consist of two polypeptide chains, an a or heavy chain and a non-covalently associated protein, b-2-Microglobulin. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A is a MHC class I heavy chain molecule that plays a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and HLA-C are proteins encoded by closely related genes that also exist in the MHC class I. HLA-E belongs to the HLA class I heavy chain paralogs. HLA-E is a heterodimer consisting of a heavy chain and a light chain. The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2, kappa

免疫原:

A portion of amino acids 1-150 from human HLAE protein was used as the immunogen for the HLA-E antibody.

克隆性:

Monoclonal (mouse origin)