HSP47 Antibody: ATTO 390-单抗-深圳欣博盛生物科技有限公司

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HSP47 Antibody: ATTO 390

品牌：Stressmarq

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说明书

折扣/货期

货号：SMC-203B-A390

规格：200 µg

目录价：￥5972.4

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

HSP47 Antibody: ATTO 390

别名:

SerpinH1 Antibody, Colligin Antibody, Gp46 Antibody, serine proteinase inhibitor Antibody, cysteine proteinase inhibitor Antibody, collagen binding protein Antibody

产品描述:

Mouse Anti-Human HSP47 Monoclonal IgG1 Kappa

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB | ICC/IF

靶标/特异性:

Detects 47kDa.

同种型:

IgG1 Kappa

推荐稀释度:

WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Human HSP47, full length

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

1C4-1A6

纯化方式:

Protein G Purified

偶联:

ATTO 390

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

HSP47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of HSP47 around fibrotic lesions (1). The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since HSP47 binds a single substrate (2). Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils (3).

Accession #:

NP_001193943