Human CBFb protein, His tag-其他重组蛋白-深圳欣博盛生物科技有限公司

首页产品中心其他重组蛋白

Human CBFb protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67268-pro

规格：50μg

目录价：￥4100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human CBFb protein, His tag

别名:

core-binding factor subunit beta , PEBP2B

克隆号:

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

E. coli

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

20mM MES buffer, 10% Glycerol, 0.1mM PMSF, no preservatives.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

您可能感兴趣的产品

Cullin 2/RBX1 Complex (human, recombinant)

货号：45183-100 µg

CRBN/DDB1 Complex (human, recombinant)

货号：45180-100 µg

Cbl-c (human, recombinant)

货号：45177-100 µg

BTBD11 (human, recombinant)

货号：45175-10 µg

BACH2 (human, recombinant)

货号：45171-10 µg

ARMC5 (human, recombinant)