| 货号:GTX03793-pro | 规格:20μg | 目录价:¥8300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Human EPO protein (active)
别名:
erythropoietin , DBAL , ECYT5 , EP , MVCD2
产品描述:
The bio-activity was determined by dose-dependent stimulation of the proliferation of TF-1 cells. The ED50 < 0. 2ng/mL, corresponding to a specific activity of >5000000 Unit/mg.
实验应用:
Functional Assay
克隆号:
偶联:
Unconjugated
产品浓度:
表达系统:
HEK293 cells
保存温度:
Store at -20ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Batch dependent (please contact us for details)
生产商:
GeneTex
功能与背景:
This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
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