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折扣/货期| 货号：GTX67408-pro | 规格：100μg | 目录价：￥7600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Human Glucokinase protein, His tag
别名:
glucokinase , FGQTL3 , GK , GLK , HHF3 , HK4 , HKIV , HXKP , LGLK , MODY2
克隆号:
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 10% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]
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