Human IL15 protein, His tag (active)-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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Human IL15 protein, His tag (active)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX00088-pro

规格：10μg

目录价：￥4400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human IL15 protein, His tag (active)

别名:

interleukin 15 , IL-15

实验应用:

Functional Assay

克隆号:

偶联:

Unconjugated

产品浓度:

表达系统:

HEK293 cells

保存温度:

For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]

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