| 货号:GTX67952-pro | 规格:100μg | 目录价:¥4100 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Human MAPKAP Kinase 3 protein, His tag
别名:
mitogen-activated protein kinase-activated protein kinase 3 , 3PK , MAPKAP-K3 , MAPKAP3 , MAPKAPK-3 , MDPT3 , MK-3
克隆号:
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 200mM NaCl, 20% Glycerol, 1mM DTT, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
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