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Human MBD3 protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX68540-pro

规格：50μg

目录价：￥5500

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human MBD3 protein, His tag

别名:

methyl-CpG binding domain protein 3

克隆号:

偶联:

Unconjugated

产品浓度:

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

E. coli

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

20mM Tris-HCl, 200mM NaCl, 40% Glycerol, 1mM DTT, 1mM EDTA, no preservatives.

生产商:

GeneTex

功能与背景:

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

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