Human MEK3 protein, His tag-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human MEK3 protein, His tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67684-pro

规格：10μg

目录价：￥4100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human MEK3 protein, His tag

别名:

mitogen-activated protein kinase kinase 3 , MAPKK3 , MEK3 , MKK3 , PRKMK3 , SAPKK-2 , SAPKK2

克隆号:

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

E. coli

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

20mM Tris-HCl, 10% Glycerol, no preservatives.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

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