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折扣/货期| 货号：38516-1 mg | 规格：1 mg | 目录价：￥428.8 |
| 货号：38516-10 mg | 规格：10 mg | 目录价：￥2572.8 |
| 货号：38516-25 mg | 规格：25 mg | 目录价：￥5360 |
| 货号：38516-5 mg | 规格：5 mg | 目录价：￥1393.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Siremadlin
别名:
HDM201|NVP-HDM201
产品描述:
A MDM2-p53 protein-protein interaction inhibitor (IC50 = 0.21 nM); selectively inhibits the MDM2-p53 protein-protein interaction over MDM4-p53, YAP1-TEAD4, PCSK9-LDLR, and Bcl-2-Bak interactions in TR-FRET assays (IC50s = 3.3, >150, >50, and >50 µM, respectively); inhibits the growth of SJSA-1 cells (GI50 = 38 nM); induces apoptosis in SJSA-1 cells at 100 nM; induces tumor regression and prevents tumor regrowth in an SJSA-1 rat xenograft model and an HSAX2655 PDX rat liposarcoma model at 27 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
555.4122
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1448867-41-1
分子式:
C26H24Cl2N6O4
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