Human PD-L1 protein, mouse IgG1 Fc tag (active)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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Human PD-L1 protein, mouse IgG1 Fc tag (active)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX01279-pro

规格：100μg

目录价：￥3700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human PD-L1 protein, mouse IgG1 Fc tag (active)

别名:

B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1

实验应用:

Functional Assay

克隆号:

偶联:

Unconjugated

产品浓度:

表达系统:

HEK293 cells

保存温度:

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Batch dependent (please contact us for details)

生产商:

GeneTex

功能与背景:

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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