Human PKA C alpha protein, GST tag-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human PKA C alpha protein, GST tag

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX67670-pro

规格：10μg

目录价：￥4100

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human PKA C alpha protein, GST tag

别名:

protein kinase cAMP-activated catalytic subunit alpha , PKACA , PPNAD4

克隆号:

偶联:

Unconjugated

产品浓度:

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

表达系统:

Baculovirus

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

dry ice

产品形式:

Liquid

存储溶液:

PBS, 10% Glycerol, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015]

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