| 货号:41160-10 mg | 规格:10 mg | 目录价:¥2331.6 |
| 货号:41160-25 mg | 规格:25 mg | 目录价:¥5480.6 |
| 货号:41160-5 mg | 规格:5 mg | 目录价:¥1460.6 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAY-805
产品描述:
A USP21 inhibitor (IC50 = 6 nM in an HTRF assay); selective for USP21 over a panel of 44 DUBs and 68 other enzymes, receptors, transporters, and ion channels at 10 µM but does inhibit AChE and adenosine transporters by 72 and 62%, respectively; selective for USP21 over a panel of six cysteine proteases (IC50s = >20 µM for all) and a panel of >360 kinases at 10 µM but does inhibit PRAK (IC50 = 8.6 µM); induces activation of NF-κB in a reporter assay using HEK293T cells (EC50 = 17 nM); reduces spheroid formation in HCT-15 and HT-29 cells (IC50s = 1.6 and 7.5 µM, respectively); decreases disease severity and spleen, liver, kidney, and lung viral titers in a mouse model of EV71 infection at 5 and 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
507.6
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2925481-88-3
分子式:
C24H28F3N5O2S
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