Human Vitamin D Receptor protein, His tag-其他重组蛋白-深圳欣博盛生物科技有限公司

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Human Vitamin D Receptor protein, His tag

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX00163-pro

规格：10μg

目录价：￥4400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Human Vitamin D Receptor protein, His tag

别名:

vitamin D receptor , NR1I1 , PPP1R163

实验应用:

Functional Assay

克隆号:

偶联:

Unconjugated

产品浓度:

表达系统:

E. coli

保存温度:

For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 100mM NaHCO₃ and 500mM NaCl (pH8.3) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 100mM NaHCO₃ (pH8.3), 500mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.

生产商:

GeneTex

功能与背景:

This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]

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