深圳欣博盛生物科技有限公司 a1

iCRT3
货号:40836-10 mg 规格:10 mg 目录价:¥1568
货号:40836-25 mg 规格:25 mg 目录价:¥3055
货号:40836-5 mg 规格:5 mg 目录价:¥871
货号:40836-50 mg 规格:50 mg 目录价:¥4797
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
iCRT3
产品描述:
An inhibitor of β-catenin-responsive transcription; inhibits Wnt signaling in a reporter assay using HEK293 cells (IC50 = 8.2 nM); selective for inhibition of the protein-protein interaction between β-catenin and Tcf over the interaction between β-catenin and E-cadherin or α-catenin; inhibits neurotensin- or Wnt3a-induced increases in the proliferation of A172 and U87 glioblastoma cells at 50 µM; reduces tumor growth in an A172 mouse xenograft model at 5 mg/kg; reduces plasma levels of IL-6, TNF-α, and IL-1β, as well as AST and ALT in a mouse model of cecal ligation and puncture-induced sepsis at 5 and 10 mg/kg; reduces lung cell apoptosis and the severity of sepsis-induced lung injury in a mouse model of cecal ligation and puncture-induced sepsis at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
394.53082
产品形式:
A solid
纯度:
≥95%
CAS号:
901751-47-1
分子式:
C23H26N2O2S
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