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折扣/货期| 货号：40837-10 mg | 规格：10 mg | 目录价：￥1876 |
| 货号：40837-25 mg | 规格：25 mg | 目录价：￥3712 |
| 货号：40837-5 mg | 规格：5 mg | 目录价：￥992 |
| 货号：40837-50 mg | 规格：50 mg | 目录价：￥6914 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LMT-28
产品描述:
An inhibitor of the gp130-IL-6/IL6Rα protein-protein interaction; binds to gp130 (Kd = 7.4 µM) and selectively inhibits IL-6-induced STAT3 phosphorylation over leukemia inhibitor factor- or phorbol 12-myristate 13-acetate-induced STAT3 phosphorylation in HepG2 cells at 10, 30, or 100 µM; reduces IL-6-induced increases in the viability of GM-CSF-starved TF-1 leukemia cells at 10 to 1,000 nM; inhibits the LPS- and AGE-induced increases in mRNA encoding Rankl, as well as inhibits increases in the phosphorylation levels of gp130, Stat3, and Jak2, in mouse MC3T3-E1 osteoblasts at 100 nM; decreases joint and paw swelling, as well as serum levels of COMP, SAP, and anti-collagen II antibodies, in a mouse model of collagen-induced arthritis at 0.25 mg/kg per day; reduces bone resorption height and volume in a rat model of type 2 diabetes peri-implantitis induced by LPS, P. gingivalis, and a high-fat and high-sugar diet at 0.23 mg/kg per day p.o.
保存温度:
-20
运输温度:
-20
预期分子量:
311.4165
产品形式:
A neat oil
纯度:
≥98%
CAS号:
1239600-18-0
分子式:
C17H29NO4
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