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折扣/货期| 货号：41310-10 mg | 规格：10 mg | 目录价：￥1367 |
| 货号：41310-25 mg | 规格：25 mg | 目录价：￥2399 |
| 货号：41310-5 mg | 规格：5 mg | 目录价：￥804 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Idazoxan (hydrochloride)
别名:
RX 781094
产品描述:
An antagonist of α2-adrenergic and imidazoline I1 and I2 receptors (IC50s = 69, 66, and 61 nM, respectively); selectively binds to α2A- and α2C-ARs over α2B-ARs (Kds = 67, 69, and 407 nM, respectively), as well as α2-ARs over α1-ARs (IC50s = 0.7 and 4,000 µM, respectively); increases mean arterial pressure and decreases heart rate in rabbits from 0.1-5 mg/kg; reverses the anti-hyperalgesic activity of 2-BFI in rat models of inflammatory and neuropathic pain and the antidepressant-like activity of 2-BFI in the tail suspension test in mice; reduces L-DOPA-induced dyskinesia in a cynomolgus monkey model of MPTP-induced Parkinson’s disease at 7.5 and 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
204.22526
产品形式:
A solid
纯度:
≥95%
CAS号:
79944-56-2
分子式:
C11H12N2O2 • HCl
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