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折扣/货期| 货号：41053-1 mg | 规格：1 mg | 目录价：￥1849.2 |
| 货号：41053-10 mg | 规格：10 mg | 目录价：￥10143.8 |
| 货号：41053-25 mg | 规格：25 mg | 目录价：￥13828.8 |
| 货号：41053-5 mg | 规格：5 mg | 目录价：￥5534.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KT474
别名:
SAR444656
产品描述:
A PROTAC that drives IRAK4 degradation; induces the degradation of IRAK4 in primary mouse and rat splenocytes and isolated dog, monkey, and human PBMCs (DC50s = 4.2, 2.1, 9.2, 2.9, and 1.5 nM, respectively); selective for IRAK4 over a panel of 468 kinases at 1 µM; inhibits R-848-induced IL-8 release in isolated human PBMCs (IC50 = 3 nM); decreases ear thickness in a mouse model of imiquimod-induced psoriasis at 30 and 100 mg/kg, p.o.
保存温度:
-20
运输温度:
-20
预期分子量:
865.927206
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
2432994-31-3
分子式:
C44H49F2N11O6
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