IDH1 antibody-多抗-深圳欣博盛生物科技有限公司

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IDH1 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX105179	规格：100μl	目录价：￥4000
货号：GTX105179-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IDH1 antibody

别名:

isocitrate dehydrogenase (NADP(+)) 1, cytosolic , HEL-216 , HEL-S-26 , IDCD , IDH , IDP , IDPC , PICD

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IHC-P, IP, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human IDH1. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

2.33 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 20% Glycerol, 0.025% ProClin 300.

生产商:

GeneTex

功能与背景:

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq]

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