IGF-I(4-70) Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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IGF-I(4-70) Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：91-023

规格：0.05 mg

目录价：￥4826.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IGF-I(4-70) Recombinant Protein

别名:

Insulin-Like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IGF1, IBP1

表达系统:

E. coli

保存温度:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Lyophilized from a 0.2 um filtered solution of 300mM NaAc, pH 6.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 500mM Acetic Acid.

产地:

美国

生产商:

Prosci

功能与背景:

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids has 94% identity with mouse IGF-I and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-I in vitro.

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.05 ng/ug (0.5 IEU/ug) as determined by LAL test.

生物活性:

ED50 is greater than 200 ng/ml as determined by an IGF binding protein assay.

Accession #:

P05019

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