IGF1R alpha antibody [AMY10-105.8 (1H7)]-单抗-深圳欣博盛生物科技有限公司

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IGF1R alpha antibody [AMY10-105.8 (1H7)]

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX20986

规格：50μg

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IGF1R alpha antibody [AMY10-105.8 (1H7)]

别名:

CD221 , IGF1R , IGFIR , IGFR , JTK13 , insulin like growth factor 1 receptor , IGF1R alpha , IGF1R beta , IGF1 Receptor alpha , IGF1 Receptor beta

反应种属:

Human

宿主来源:

Mouse

实验应用:

Neutralizing/Inhibition, WB

靶标/特异性:

This antibody recognizes an epitope in the alpha subunits of IGF1R. Clone 1H7 is reported to partially block binding of IGF-I and IGF-II to IGF1 Receptor (Li et al.1993).

同种型:

IgG1

免疫原:

Purified human placental IGF-1 receptors.

克隆性:

Monoclonal

克隆号:

AMY10-105.8 (1H7)

纯化方式:

Protein G purified

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

155

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

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