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折扣/货期| 货号：GTX28093-02 | 规格：100μg | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IGF2R antibody [MEM-238] (Biotin)
别名:
CD222 , CIM6PR , CIMPR , IGF2R , M6P/IGF2R , M6PR , MPR 300 , MPR1 , MPR300 , MPRI , insulin like growth factor 2 receptor , IGF2 receptor , cation-independent M6PR , IGF-IIR
反应种属:
Human, Primate
宿主来源:
Mouse
实验应用:
FCM, IP, WB
靶标/特异性:
This antibody recognizes an epitope between amino acids 192-697 of CD222 (IGF2 receptor).
同种型:
IgG1
免疫原:
Recombinant Vaccinia virus encoding CD222.
克隆性:
Monoclonal
克隆号:
MEM-238
纯化方式:
Purified IgG
偶联:
Biotin
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
274
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
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