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折扣/货期| 货号：GTX27896 | 规格：50μg | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IKK gamma peptide
别名:
Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Gamma , Amcbx1 , Fip-3 , Fip3 , Fip3P , Ikk-Gamma , Ikkap1 , Ikkg , Imd33 , Ip , Ip1 , Ip2 , Ipd2 , Nemo , Zc2Hc9 , Ikbkg
实验应用:
Neutralizing/Inhibition
克隆号:
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store the peptide at -20ºC, stable for one year.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. Ikk gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
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