IL-15 (human) (rec.) (His)-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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IL-15 (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HR-20015-C010	规格：10 ug	目录价：￥2170
货号：CHI-HR-20015-C050	规格：50 ug	目录价：￥6160

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL-15 (human) (rec.) (His)

别名:

Interleukin-15

产品描述:

Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems. IL-15 up-regulation has a central role in the development of several autoimmune or chronic inflammatory disorders. Targeting IL-15 or its receptor may have a valuable impact on the treatment of immune-mediated diseases. IL-15 participates in the development of important immune antitumor mechanisms. It activates CD8(+) T cells, natural killer (NK) cells, NK T cells, and can promote the formation of antitumor antibodies. IL-15 can also protect T effector cells from the action of T regulatory cells and reverse tolerance to tumor-associated antigens. In pre-clinical studies IL-15 has been found to demonstrate potentiated antitumor effects following pre-association with IL-15Ralpha, or when used in combination with chemotherapy, adoptive therapy, monoclonal antibodies, and tumor vaccines.

宿主来源:

E. coli

保存温度:

+4°C

运输温度:

预期分子量:

~14kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

产地:

瑞士

纯度:

>95% (SDS-PAGE)

生物活性:

Measured by its ability to stimulate the proliferation of mouse CTLL-2 cells. The ED50 for this effect is typically 0.5ng/mL, corresponding to a specific activity of 2x 106 units/mg

内毒素水平:

<0.1EU/µg protein (LAL test; Lonza).

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