IL-1alpha (human) (rec.) (His)-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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IL-1alpha (human) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HR-20001A-C010	规格：10 ug	目录价：￥2520
货号：CHI-HR-20001A-C050	规格：50 ug	目录价：￥6580

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL-1alpha (human) (rec.) (His)

别名:

Interleukin-1alpha; IL-1F1; IL-1A

产品描述:

The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.

宿主来源:

E. coli

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized from a concentrated sterile solution containing 50mM Tris-HCl buffer (pH 8.0) and 100mM NaCl.

有效期:

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

产地: