官网链接
折扣/货期| 货号：AG-40B-0100-C010 | 规格：10 ug | 目录价：￥2280 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-36gamma (aa 13-164) (mouse) (rec.) (untagged)
别名:
Interleukin-36gamma; Interleukin-1 Family Member 9; IL-1F9
产品描述:
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~17kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS + 0.5% Trehalose.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces secretion of IL-6 in BMDCs.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
上一个:IL-36beta (aa 31-183) (mouse) (rec.) (untagged)
下一个:IL-36gamma (aa 13-164) (mouse) (rec.) (FLAG)
您可能感兴趣的产品
FGF4 (human, recombinant)
货号：42758-100 µg
Recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165)
货号：ORF.GF.VEGF165-1000
Recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165)
货号：ORF.GF.VEGF165-500
Recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165)
货号：ORF.GF.VEGF165-100
Recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165)
货号：ORF.GF.VEGF165-50
Recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165)
货号：ORF.GF.VEGF165-10
Recombinant Human Transforming Growth Factor Beta 1 (TGF-β1)
货号：ORF.GF.TGFB1-1000
Recombinant Human Transforming Growth Factor Beta 1 (TGF-β1)
货号：ORF.GF.TGFB1-500
促销活动
精品推荐
相关产品推荐
IL-15 (mutant) (human):Fc (human) (rec.)
货号：CHI-HF-21015M-C050
IL-22 (human):Fc (human) (rec.)
货号：CHI-HF-21022-C025
IL-23R (human):Fc (human) (rec.)
货号：CHI-HF-21023R-C100
IL-24 (human):Fc (human) (rec.)
货号：CHI-HF-21024-C025
IL-27 (human):Fc (human) (rec.)
货号：CHI-HF-21027-C050
IL-35 (human):Fc (human) (rec.)
货号：CHI-HF-21035-C025
复制QQ号成功，请打开QQ后添加好友进行咨询