IL-37 (human) ELISA Kit-人ELISA试剂盒-深圳欣博盛生物科技有限公司

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IL-37 (human) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45A-0041YEK-KI01	规格：96 wells	目录价：￥8160
货号：AG-45A-0041YTP-KI01	规格：2 x 96 wells	目录价：￥13440

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL-37 (human) ELISA Kit

别名:

Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1

产品描述:

IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption. A recent study indicates that IL-37 protein forms a head-to-head homodimer and this structure limits its bioactivity. Variants with mutations converting the cytokine into a monomeric form are 13 fold more active than the dimeric IL-37.

靶标/特异性:

Detects human IL-37 (monomeric and dimeric forms). Does not cross-react with human IL-33, IL-38, IL-6, IL-23, IL-24 or mouse IL-33 and IL-38.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

10pg/ml

检测范围:

0.016 to 1ng/ml

检测方法: