Nampt (Visfatin/PBEF) (human) ELISA Kit-人ELISA试剂盒-深圳欣博盛生物科技有限公司

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Nampt (Visfatin/PBEF) (human) ELISA Kit

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-45A-0006YEK-KI01	规格：96 wells	目录价：￥7680
货号：AG-45A-0006YTP-KI01	规格：2 x 96 wells	目录价：￥13680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nampt (Visfatin/PBEF) (human) ELISA Kit

别名:

Nicotinamide Phosphoribosyltransferase; PBEF1; Pre-B Cell Colony Enhancing Factor 1

产品描述:

Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohn’s disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health. Recently it was reported that Visfatin levels were higher in the unstable carotid atherosclerotic plaque than in non-atherosclerotic mammary artery secretomes, suggesting a possible link between visfatin and unstable carotid atherosclerotic plaque. Recently NAMPT extracellular (eNAMPT) has been shown to be secreted from macrophages in muscles and to triggers a proliferative signal of muscle stem cell (MusC) by binding to CCR5 located at the surface receptor of MusC.

靶标/特异性:

Detects human Nampt. Weakly cross-reacts (<15%) with mouse Nampt and rat Nampt. Does not cross-react with human adiponectin, human resistin, human vaspin or human RBP4. Has been shown to specifically detect the physiologically relevant Nampt dimer in human serum samples.

保存温度:

+4°C

运输温度:

产地:

瑞士

灵敏度:

30pg/ml

检测范围:

0.125 to 8ng/ml

检测方法:

Colorimetric

样本类型: