IL-38 (human) (rec.) (His) MultiPack-其他重组蛋白-深圳欣博盛生物科技有限公司

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IL-38 (human) (rec.) (His) MultiPack

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40A-0191Y-3010	规格：3 x 10 ug	目录价：￥5520
货号：AG-40A-0191Y-C010	规格：10 ug	目录价：￥2760

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL-38 (human) (rec.) (His) MultiPack

别名:

Interleukin-38; Interleukin-1 Family Member 10 theta; IL-1F10; FIL1 theta; FKSG75; IL-1HY2; IL1-theta; Interleukin-1 HY2; Interleukin-1 Receptor Antagonist FKSG75

产品描述:

IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 (also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma) is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 (20-152) binds to the receptor Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1; TIGIRR-2) at the surface of macrophages. Processed IL-38-activated IL1RAPL1 reduces the production of IL-6 leading to inflammation attenuation.

宿主来源:

E. coli

产品浓度:

After reconstitution:for 10µg size: 0.1mg/ml

保存温度:

+4°C

运输温度:

预期分子量:

~18kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized. In 50mM TRIS-Cl, pH 8.0, containing 150mM NaCl.

有效期:

Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.After reconstitution, prepare aliquots and store at -20°C.

产地:

瑞士

纯度:

>95% (SDS-PAGE)

内毒素水平:

<1EU/µg purified protein (LAL test; Lonza).

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