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折扣/货期| 货号：40-619 | 规格：0.02 mg | 目录价：￥6493.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-4 Recombinant Protein
别名:
Il-4, BSF-1, Il-4, Interleukin-4, B-cell IgG differentiation factor, IL-4
表达系统:
E. coli
保存温度:
The lyophilized IL-4 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is =2.0 ng/mL, corresponding to a specific activity of = 5 x 105 units/mg
Accession #:
NP_067258.1
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