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折扣/货期| 货号：91-007 | 规格：0.05 mg | 目录价：￥10126.35 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-6 Recombinant Protein
别名:
Interleukin-6, IL-6, B-Cell Stimulatory Factor 2, BSF-2, CTL Differentiation Factor, CDF, Hybridoma Growth Factor, Interferon Beta-2, IFN-Beta-2, IL6, IFNB2
表达系统:
E. coli
保存温度:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 5.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
产地:
美国
生产商:
Prosci
功能与背景:
Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
纯度:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
生物活性:
Recombinant IL-6 is fully biologically active when compared to standards.
ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of human TF-1 cells.
Specific Activity of 5.0 x 107 IU/mg.
ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of human TF-1 cells.
Specific Activity of 5.0 x 107 IU/mg.
Accession #:
P05231
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