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折扣/货期| 货号：CHI-HF-22008-C010 | 规格：10 ug | 目录价：￥2030 |
| 货号：CHI-HF-22008-C050 | 规格：50 ug | 目录价：￥3570 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL-8 (human):Fc (human) (rec.) (non-lytic)
别名:
Interleukin-8; CXCL8; C-X-C Motif Chemokine 8; Emoctakin; GCP-1; LAI; MDNCF; MONAP; NAP-1; NCF; TCF
产品描述:
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes and various tumor cell lines, produce IL-8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS and viruses. IL-8 has a wide range of other proinflammatory effects. It is a potent chemoattractant for neutrophils and causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a co-mitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro.
宿主来源:
CHO cells
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Shows the biological function of the IL-8 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
促销活动
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