IL2 Receptor alpha antibody [PC61.5] (APC-Cy7)-单抗-深圳欣博盛生物科技有限公司

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IL2 Receptor alpha antibody [PC61.5] (APC-Cy7)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX01472-15

规格：100μg

目录价：￥4900

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IL2 Receptor alpha antibody [PC61.5] (APC-Cy7)

产品描述:

The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells. The PC61.5 antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25. This clone has also been reported for depletion of Treg cells in vivo.

反应种属:

Mouse

宿主来源:

Rat

实验应用:

FCM

同种型:

IgG1

克隆性:

Monoclonal

克隆号:

PC61.5