深圳欣博盛生物科技有限公司 a1

IL21 Receptor antibody
货号:GTX13321 规格:50μg 目录价:¥4700
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IL21 Receptor antibody
别名:
CD360,IL21R,NILR,interleukin 21 receptor,IL21-R,IL21 Receptor
反应种属:
Human, Mouse
宿主来源:
Goat
实验应用:
ELISA, IHC
同种型:
IgG
免疫原:
Synthetic peptide CILEMWNLHPSTLTLTWQDQYEELKDEATS corresponding to 35-65 residues of N-terminus of human IL-21 receptor.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
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